Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases.
نویسندگان
چکیده
Enzymatic recognition of SeLNA nucleotides was investigated. KOD XL DNA polymerase was found to be an efficient enzyme in primer extension reactions. Polymerase chain reaction (PCR) amplification of SeLNA-modified DNA templates was also efficiently achieved by Phusion and KOD XL DNA polymerases.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 89 شماره
صفحات -
تاریخ انتشار 2012